Testing of renin and aldosterone levels in the blood – Arterial hypertension package
What is renin?
Renin is an enzyme that controls the production of aldosterone. Aldosterone is a hormone that plays an important role in maintaining normal concentrations of sodium and potassium in the blood, as well as in controlling blood volume and blood pressure. The test measures the amount of renin in the blood.
Why is the study of renin levels in the blood performed?
Plasma renin activity is measured as part of the diagnosis and treatment of hypertension (high blood pressure). Patients with primary hyperaldosteronism have increased aldosterone production associated with decreased plasma renin activity. Patients with secondary hyperaldosteronism (i.e., caused by renal disease or renovascular hypertension) have increased plasma renin and aldosterone levels.
What is aldosterone?
Aldosterone is a steroid hormone secreted by the adrenal cortex. It is part of the renin-angiotensin-aldosterone system and is an integral part of the complex mechanisms that control water and electrolyte balance in the body. Its action affects sodium, potassium and water levels through the excretory and circulatory systems.
What is the function of aldosterone?
The main function of aldosterone is to increase reabsorption (reverse suction) in the last part of the distal nephron duct and collecting ducts. When working specifically at this site, the hormone binds to the mineralocorticoid receptors of the distal duct. Once aldosterone binds to the receptors, the permeability of the distal tubular membrane increases. This facilitates the passage of potassium and sodium.
What is the preparation for testing renin levels in the blood?
The doctor may advise the patient to temporarily stop (2 to 4 weeks before the test) medications that may interfere with the test (such as beta-blockers, 2-agonists, non-steroidal anti-inflammatory drugs). Adherence to a normal, balanced, low-sodium diet (about 3 g per day) for 3 days before the test is recommended. On the day of the procedure, the patient should not consume foods or beverages that contain caffeine.
Testing of renin and aldosterone levels in the blood – Arterial hypertension package – price BGN 78
- Results within 15 working days;
- A sampling fee is payable locally.
