Epstein-Barr virus (EBV) DNA testing
Epstein-Barr virus, also known as human herpes virus 4, is a widespread double-stranded DNA herpes virus. It is the causative agent of infectious mononucleosis (‘mono’ or ‘glandular fever’).
Who are the risk groups for developing infectious mononucleosis?
At higher risk of developing infectious mononucleosis are young people aged between 15 and 30 years, medical students, medical trainees, nurses, caregivers. Virtually anyone who comes into contact with large numbers of people on a regular basis is at increased risk, and for this reason the disease is most common at school age.
The main symptoms are:
- Temperature;
- Sore throat with enlarged tonsils that does not improve after antibiotic treatment;
- Rash on the skin;
- Swollen lymph nodes on the neck and armpits;
- Headache;
- Fatigue;
- Soft and enlarged spleen
If infection with EBV occurs in early childhood, the infection may proceed completely asymptomatic or with the development of only some of the symptoms. In these cases, no diagnosis is made and the infection passes spontaneously. If serological testing (evidence of antibodies to the virus in the serum) is done after a while, it can be proven that the person has had an encounter with the virus.
Tests to prove EBV
- To detect specific antibodies to certain antigens of the virus by specific immunological methods – ELISA, etc.;
- To detect viral DNA by molecular biology methods, e.g. Real time PCR.
Both types of tests are appointed and interpreted by a specialist doctor. They are necessary to prove the infection itself.
A large proportion of people in adulthood have antibodies to EBV, which indicate a past infection and therefore the presence of immunity.
EPSTAIN-BAR VIRUS (EBV) – DNA testing – price 170 BGN.
- An additional sampling fee is payable.
- Results within 5 working days.
